General name: flunixin meglumine granules

Commodity name: Pujia

English Name: fluixin meglumine granules

Hanyu Pinyin: funixin pujia'an Keli

Flunixin meglumine

This product is off white or light yellow particles.

Pharmacodynamics: flunixine meglumine is a powerful cyclooxygenase inhibitor with analgesic, antipyretic, anti-inflammatory and anti rheumatic effects. The analgesic effect is caused by blocking the transmission of pain impulses by inhibiting the synthesis of peripheral exemplarin or its pain sensitizing substance or their joint action. The anti-inflammatory effect of peripheral tissue may be caused by inhibiting cyclooxygenase, reducing the formation of prostaglandin precursors, and inhibiting local inflammatory reaction caused by other mediators. Flunixin meglumine does not affect gastrointestinal peristalsis in horses, but may improve hemodynamics in animals with septic shock. Pharmacokinetics: after a single intramuscular injection in pigs (2.2mg/kg body weight), the plasma elimination half-life is 3 ~ 4 hours, the peak concentration is 2.94 ug/ml, and the peak time is 0.4 hours. The drug can still be detected in the blood 18 hours after administration. The apparent distribution volume was 2.0l/kg, and the bioavailability of a single neck injection was 87%.

(1) When used together with other non steroidal anti-inflammatory drugs, it will aggravate the toxic and side effects on the gastrointestinal tract, such as ulcers, bleeding, etc.

(2) Due to the high binding rate of plasma protein, when combined with other drugs, flunixin meglumine may replace other drugs combined with plasma protein or be replaced by other drugs, so that the replaced drugs have enhanced effect and even toxicity.

Antipyretic and analgesic anti-inflammatory drugs. It is used for febrile, inflammatory diseases, muscle pain and soft tissue pain of livestock and small animals.

Calculated by this product. Oral administration: once, 40mg for dogs and cats per 1kg body weight, 1-2 times a day, for no more than 5 days.

Long term high-dose use of this product may cause gastric ulcer and renal function damage in animals.

(1) Animals with peptic ulcer should be used with caution.

(2) Do not use it together with other non steroidal anti-inflammatory drugs.

No need to formulate.

C₁₄H₁₁F₃N₂O₂5%

Keep in a dark and airtight place.