General name: florfenicol soluble powder

English Name: florfenicol soluble powder

Chinese Pinyin: fubennikao kerongxing Fen

Florfenicol

This product is white or off white powder.

Pharmacodynamics: florfenicol is a broad-spectrum amide alcohol antibiotic and an antibacterial agent. It plays a role by combining with ribosomal 50S subunit to inhibit the synthesis of bacterial proteins. It has strong antibacterial activity against a variety of gram-positive and Gram-negative bacteria. Pasteurella haemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae are highly sensitive to florfenicol. In vitro, the antibacterial activity of florfenicol against many microorganisms is similar to or stronger than that of thiamphenicol. Some bacteria resistant to amidol due to acetylation, such as Escherichia coli and Klebsiella pneumoniae, may still be sensitive to florfenicol. It is mainly used for bacterial diseases of pigs, chickens and fish caused by sensitive bacteria, such as respiratory diseases of cattle and pigs caused by Pasteurella haemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae. Typhoid and paratyphoid fever caused by Salmonella, chicken cholera, chicken pullorum, colibacillosis, etc; Fish bacterial septicemia, enteritis, erythroderma, etc. caused by Pasteurella, Vibrio, Staphylococcus aureus, Aeromonas hydrophila, enteritis bacteria, etc.

Pharmacokinetics: florfenicol is absorbed rapidly after oral administration, and the therapeutic concentration can be reached in the blood after about 1 hour, and the peak blood concentration can be reached within 1~3 hours. The bioavailability is more than 80%. Florfenicol is widely distributed in animals and can penetrate the blood-brain barrier. It is mainly discharged from urine in its original form, and a small amount is discharged with feces.

(1) Macrolides and lincomrades have the same action target as this product, both of which are combined with 50S subunit of bacterial ribosome, and can produce mutual antagonism when combined.

(2) It may antagonize the bactericidal activity of penicillins or aminoglycosides, but it has not been proved in animals.

Amide alcohol antibiotics. It is used to treat bacterial infection caused by chicken sensitive bacteria.

Calculated by this product. Mixed drinking: 0.33g~0.66g chicken per 1L of water for 3-5 days.

This product has strong immunosuppressive effect when it is used above the recommended dose

(1) The laying period of laying hens is forbidden.

(2) It is forbidden for animals with severe immune function impairment during the vaccination period.

Chicken 5 days.

30%

Keep it in a dry place.